Andrew Godwin

Articles in Scholarly Journals [Incomplete List]

  1. Ovca1, a candidate gene of the genetic modifier ofTp53,Mop2, affects mouse embryonic lethality
    Genes, Chromosomes and Cancer, vol. 47, no. 4, pp. 315–325, 2008
  2. Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner
    Gynecologic Oncology, 2008
  3. Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk
    Human Molecular Genetics, vol. 17, no. 9, pp. 1336–1348, 2008
  4. Promoter Hypermethylation of the PALB2 Susceptibility Gene in Inherited and Sporadic Breast and Ovarian Cancer
    Cancer Research, vol. 68, no. 4, pp. 998–1002, 2008
  5. The Differential Role of L1 in Ovarian Carcinoma and Normal Ovarian Surface Epithelium
    Cancer Research, vol. 68, no. 4, pp. 1110–1118, 2008
  6. AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Consortium of Investigators of Modifiers of BRCA1/2 Study
    Cancer Epidemiology Biomarkers & Prevention, vol. 16, no. 7, pp. 1416–1421, 2007
  7. BRCA2 Mutation-associated Breast Cancers Exhibit a Distinguishing Phenotype Based on Morphology and Molecular Profiles From Tissue Microarrays
    The American Journal of Surgical Pathology, vol. 31, no. 1, pp. 121–128, 2007
  8. Nestin Is Expressed in the Basal/Myoepithelial Layer of the Mammary Gland and Is a Selective Marker of Basal Epithelial Breast Tumors
    Cancer Research, vol. 67, no. 2, pp. 501–510, 2007
  9. MicroRNA-34b and MicroRNA-34c Are Targets of p53 and Cooperate in Control of Cell Proliferation and Adhesion-Independent Growth
    Cancer Research, vol. 67, no. 18, pp. 8433–8438, 2007
  10. Prostate Cancer Risk Assessment Program: A 10-Year Update of Cancer Detection
    The Journal of Urology, vol. 178, no. 5, pp. 1920–1924, 2007
  11. Genetic and functional analysis ofCHEK2 (CHK2) variants in multiethnic cohorts
    International Journal of Cancer, vol. 121, no. 12, pp. 2661–2667, 2007
  12. Prominent expression of metalloproteinases in early stages of ovarian tumorigenesis
    Molecular Carcinogenesis, vol. 46, no. 2, pp. 130–143, 2007
  13. A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancer
    Cancer, vol. 109, no. 7, pp. 1323–1330, 2007
  14. Intronic alterations inBRCA1 andBRCA2: effect on mRNA splicing fidelity and expression
    Human Mutation, vol. 27, no. 5, pp. 427–435, 2006
  15. Molecular genetic evidence that endometriosis is a precursor of ovarian cancer
    International Journal of Cancer, vol. 119, no. 3, pp. 556–562, 2006
  16. Mass spectrometric identification of serine hydrolase OVCA2 in the medulloblastoma cell line DAOY
    Cancer Letters, vol. 241, no. 2, pp. 235–249, 2006
  17. Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations☆
    Gynecologic Oncology, vol. 103, no. 2, pp. 719–728, 2006
  18. BRCA1-associated complexes: new targets to overcome breast cancer radiation resistance
    Expert Review of Anticancer Therapy, vol. 6, no. 2, pp. 187–196, 2006
  19. Alterations of the Tumor Suppressor Gene ARLTS1 in Ovarian Cancer
    Cancer Research, vol. 66, no. 21, pp. 10287–10291, 2006
  20. Therapeutic Effect of Imatinib in Gastrointestinal Stromal Tumors: AKT Signaling Dependent and Independent Mechanisms
    Cancer Research, vol. 66, no. 10, pp. 5477–5486, 2006
  21. BRCC36 Is Essential for Ionizing Radiation-Induced BRCA1 Phosphorylation and Nuclear Foci Formation
    Cancer Research, vol. 66, no. 10, pp. 5039–5046, 2006
  22. White Spot Syndrome Virus Open Reading Frame 222 Encodes a Viral E3 Ligase and Mediates Degradation of a Host Tumor Suppressor via Ubiquitination
    Journal of Virology, vol. 80, no. 8, pp. 3884–3892, 2006
  23. The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 1, pp. 76–79, 2006
  24. BRCA1 and BRCA2 Mutation Carriers, Oral Contraceptive Use, and Breast Cancer Before Age 50
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 10, pp. 1863–1870, 2006
  25. No Increased Risk of Breast Cancer Associated with Alcohol Consumption among Carriers of BRCA1 and BRCA2 Mutations Ages <50 Years
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 8, pp. 1565–1567, 2006
  26. Analysis of KIT Mutations in Sporadic and Familial Gastrointestinal Stromal Tumors: Therapeutic Implications through Protein Modeling
    Clinical Cancer Research, vol. 11, no. 10, pp. 3668–3677, 2005
  27. Phase II Study of Gefitinib in Patients with Relapsed or Persistent Ovarian or Primary Peritoneal Carcinoma and Evaluation of Epidermal Growth Factor Receptor Mutations and Immunohistochemical Expression: A Gynecologic Oncology Group Study
    Clinical Cancer Research, vol. 11, no. 15, pp. 5539–5548, 2005
  28. Enhanced Counseling for Women Undergoing BRCA1/2 Testing: Impact on Subsequent Decision Making About Risk Reduction Behaviors
    Health Education & Behavior, vol. 32, no. 5, pp. 654–667, 2005
  29. BMC Cancer, vol. 5, no. 1, p. 64, 2005
  30. Loss of TNF-α-regulated COX-2 expression in ovarian cancer cells
    Oncogene, vol. 24, no. 54, Article ID 1208943, 11 pages, 2005
  31. Familial Cancer Associated with a Polymorphism in ARLTS1
    New England Journal of Medicine, vol. 352, no. 16, pp. 1667–1676, 2005
  32. The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers
    Carcinogenesis, vol. 27, no. 3, pp. 599–605, 2005
  33. Molecular research directions in the management of gastrointestinal stromal tumors
    Current Treatment Options in Oncology, vol. 6, no. 6, pp. 473–486, 2005
  34. Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells
    Developmental Biology, vol. 286, no. 2, pp. 574–586, 2005
  35. Proteome Changes in Ovarian Epithelial Cells Derived from Women with BRCA1 Mutations and Family Histories of Cancer
    Molecular & Cellular Proteomics, vol. 4, no. 2, pp. 156–168, 2004
  36. Identification of a second G–C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1
    Oncogene, vol. 23, no. 22, Article ID 1207504, 8 pages, 2004
  37. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth
    Oncogene, vol. 23, no. 34, Article ID 1207721, 4 pages, 2004
  38. Focus on epithelial ovarian cancer
    Cancer Cell, vol. 5, no. 1, pp. 19–24, 2004
  39. Tumor Necrosis Factor- -Induced Matrix Proteolytic Enzyme Production and Basement Membrane Remodeling by Human Ovarian Surface Epithelial Cells: Molecular Basis Linking Ovulation and Cancer Risk
    Cancer Research, vol. 64, no. 4, pp. 1534–1540, 2004
  40. Expression of constitutively activated EGFRvlll in non-small cell lung cancer
    Cancer Science, vol. 94, no. 1, pp. 50–56, 2003
  41. Molecular Biology, vol. 37, no. 4, pp. 486–494, 2003
  42. Regulation of BRCC, a Holoenzyme Complex Containing BRCA1 and BRCA2, by a Signalosome-like Subunit and Its Role in DNA Repair
    Molecular Cell, vol. 12, no. 5, pp. 1087–1099, 2003
  43. Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27
    Proceedings of the National Academy of Sciences, vol. 100, no. 10, pp. 5956–5961, 2003
  44. The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene
    Proceedings of the National Academy of Sciences, vol. 100, no. 20, pp. 11517–11522, 2003
  45. Altered expression of the septin gene,SEPT9, in ovarian neoplasia
    The Journal of Pathology, vol. 201, no. 4, pp. 581–588, 2003
  46. Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies
    Cancer, vol. 98, no. 12, pp. 2607–2623, 2003
  47. OVCA2 is downregulated and degraded during retinoid-induced apoptosis
    International Journal of Cancer, vol. 99, no. 2, pp. 185–192, 2002
  48. DNA array-based method for detection of large rearrangements in theBRCA1 gene
    Genes, Chromosomes and Cancer, vol. 35, no. 3, pp. 232–241, 2002
  49. Comparison of DNA- and RNA-Based Methods for Detection of TruncatingBRCA1 Mutations
    Human Mutation, vol. 20, no. 1, pp. 65–73, 2002
  50. Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity
    Cancer, vol. 94, no. 9, pp. 2380–2392, 2002
  51. Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis
    Cancer, vol. 95, no. 8, pp. 1802–1815, 2002
  52. Elevated JNK activation contributes to the pathogenesis of human brain tumors
    Oncogene, vol. 21, no. 33, Article ID 1205593, 8 pages, 2002
  53. gamma -Synuclein Promotes Cancer Cell Survival and Inhibits Stress- and Chemotherapy Drug-induced Apoptosis by Modulating MAPK Pathways
    Journal of Biological Chemistry, vol. 277, no. 38, pp. 35050–35060, 2002
  54. Ras/MAPK Pathway Confers Basement Membrane Dependence upon Endoderm Differentiation of Embryonic Carcinoma Cells
    Journal of Biological Chemistry, vol. 277, no. 43, pp. 40911–40918, 2002
  55. Decreased Expression of Retinol-Binding Proteins is Associated with Malignant Transformation of the Ovarian Surface Epithelium
    DNA and Cell Biology, vol. 21, no. 1, pp. 11–19, 2002
  56. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
    Human Molecular Genetics, vol. 10, no. 26, pp. 3001–3007, 2001
  57. Disabled-2 Mediates c-Fos Suppression and the Cell Growth Regulatory Activity of Retinoic Acid in Embryonic Carcinoma Cells
    Journal of Biological Chemistry, vol. 276, no. 50, pp. 47303–47310, 2001
  58. Pharmacogenetics, vol. 11, no. 7, pp. 635–638, 2001
  59. Identification in the Human Candidate Tumor Suppressor Gene HIC-1 of a New Major Alternative TATA-less Promoter Positively Regulated by p53
    Journal of Biological Chemistry, vol. 276, no. 5, pp. 3078–3089, 2000
  60. Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary
    Cancer, vol. 88, no. 9, pp. 2154–2163, 2000
  61. Identification and Structural Analysis of Human RBM8A and RBM8B: Two Highly Conserved RNA-Binding Motif Proteins That Interact with OVCA1, a Candidate Tumor Suppressor
    Genomics, vol. 69, no. 1, pp. 54–62, 2000
  62. Telomeric Instability and Reduced Proliferative Potential in Ovarian Surface Epithelial Cells from Women with a Family History of Ovarian Cancer
    Gynecologic Oncology, vol. 73, no. 2, pp. 229–236, 1999
  63. Novel germline BRCA1 mutation (155del4) in an African American with early-onset breast cancer
    Human Mutation, vol. 14, no. 6, pp. 545–545, 1999
  64. Modification of BRCA1-Associated Breast Cancer Risk by the Polymorphic Androgen-Receptor CAG Repeat
    The American Journal of Human Genetics, vol. 64, no. 5, pp. 1371–1377, 1999
  65. Nature Genetics, vol. 23, no. 3, pp. 266–268, 1999
  66. Chromosome Research, vol. 7, no. 7, pp. 531–540, 1999
  67. Genome scanning detects amplification of the cathepsin B gene (CtsB) in transformed rat ovarian surface epithelial cells
    Journal of the Society for Gynecologic Investigation, vol. 6, no. 1, pp. 32–40, 1999
  68. Nature Genetics, vol. 20, no. 1, pp. 13–14, 1998
  69. Mutation detection using a novel plant endonuclease
    Nucleic Acids Research, vol. 26, no. 20, pp. 4597–4602, 1998
  70. Haplotype and Phenotype Analysis of Nine Recurrent BRCA2 Mutations in 111 Families: Results of an International Study
    The American Journal of Human Genetics, vol. 62, no. 6, pp. 1381–1388, 1998
  71. Cloning and Localization of a Human Diphthamide Biosynthesis-like Protein-2 Gene,DPH2L2
    Genomics, vol. 52, no. 2, pp. 186–191, 1998
  72. Molecular Cloning and Characterization ofLOH11CR2A,a New Gene within a Refined Minimal Region of LOH at 11q23
    Genomics, vol. 46, no. 2, pp. 217–222, 1997
  73. Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization
    Genes, Chromosomes and Cancer, vol. 18, no. 2, pp. 115–125, 1997
  74. Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24, and 20q13 in human ovarian carcinomas
    Genes, Chromosomes and Cancer, vol. 20, no. 4, pp. 320–328, 1997
  75. Variability in loss of constitutional heterozygosity across loci and among individuals: Association with candidate genes in ductal breast carcinoma
    Molecular Carcinogenesis, vol. 17, no. 3, pp. 117–125, 1996
  76. Autonomy of the epithelial phenotype in human ovarian surface epithelium: Changes with neoplastic progression and with a family history of ovarian cancer
    International Journal of Cancer, vol. 69, no. 6, pp. 429–436, 1996
  77. Early ovarian cancer: A review of its genetic and biologic factors, detection, and treatment
    Current Problems in Cancer, vol. 20, no. 2, pp. 86–137, 1996
  78. Increased DT-diaphorase expression and cross-resistance to mitomycin C in a series of cisplatin-resistant human ovarian cancer cell lines
    Biochemical Pharmacology, vol. 52, no. 1, pp. 21–27, 1996
  79. Microscopic Benign and Invasive Malignant Neoplasms and a Cancer-Prone Phenotype in Prophylactic Oophorectomies
    Journal of the National Cancer Institute, vol. 88, no. 24, pp. 1810–1820, 1996
  80. A Grb2-associated docking protein in EGF- and insulin-receptor signalling
    Nature, vol. 379, no. 6565, Article ID 379560a0, 4 pages, 1996
  81. BRCA2 germline mutations in male breast cancer cases and breast cancer families
    Nature Genetics, vol. 13, no. 1, Article ID ng0596-123, 2 pages, 1996
  82. Glutathione and Drug Resistance
    Cancer Investigation, vol. 14, no. 2, pp. 158–168, 1996
  83. Retroviral-like sequences specifically expressed in the rat ovary detect genetic differences between normal and transformed rat ovarian surface epithelial cells
    Endocrinology, vol. 136, no. 10, pp. 4640–4649, 1995
  84. Expression of two mucin antigens in cultured human ovarian surface epithelium: Influence of a family hostory of ovarian cancer*1
    American Journal of Obstetrics and Gynecology, vol. 173, no. 2, pp. 558–565, 1995
  85. Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines
    Biochemical Pharmacology, vol. 47, no. 4, pp. 689–697, 1994
  86. Screening, Imaging, and Early Diagnosis of Ovarian Cancer
    Clinical Obstetrics and Gynecology, vol. 37, no. 2, pp. 377–391, 1994
  87. AKT2, A Putative Oncogene Encoding a Member of a Subfamily of Protein- Serine/Threonine Kinases, is Amplified in Human Ovarian Carcinomas
    Proceedings of the National Academy of Sciences, vol. 89, no. 19, pp. 9267–9271, 1992
  88. High Resistance to Cisplatin in Human Ovarian Cancer Cell Lines is Associated with Marked Increase of Glutathione Synthesis
    Proceedings of the National Academy of Sciences, vol. 89, no. 7, pp. 3070–3074, 1992
  89. Elevation of glucose transporter, c-myc, and transin RNA levels by Ha-rasT24 is independent of its effect on the cell cycle
    Molecular Carcinogenesis, vol. 4, no. 4, pp. 275–285, 1991
  90. In vitro and in vivo regulation of liver epithelial cells carrying a metallothionein-rasT24 fusion gene
    Molecular Carcinogenesis, vol. 1, no. 2, pp. 89–95, 1988
  91. MTrasT24, a Metallothionein-ras Fusion Gene, Modulates Expression in Cultured Rat Liver Cells of Two Genes Associated with in vivo Liver Cancer
    Proceedings of the National Academy of Sciences, vol. 85, no. 2, pp. 344–348, 1988