Emanuel Petricoin
Personal Home Page
http://www.gmu.edu/departments/lifesciences/proteomics/petricoin.htm
Articles in Scholarly Journals [Incomplete List]
- A New Scientific Journal Linked to a Genetic Database: Towards a Novel Publication Modality
Human Genomics and Proteomics, vol. 2009, Article ID 597478, 2 pages, 2009 - Smart Hydrogel Particles: Biomarker Harvesting: One-Step Affinity Purification, Size Exclusion, and Protection against Degradation
Nano Letters, vol. 8, no. 1, pp. 350–361, 2008 - Human Proteinpedia enables sharing of human protein data
Nature Biotechnology, vol. 26, no. 2, Article ID nbt0208-164, 3 pages, 2008 - Proteins, drug targets and the mechanisms they control: the simple truth about complex networks
Nature Reviews Drug Discovery, vol. 6, no. 11, Article ID nrd2381, 9 pages, 2007 - Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition
Oncogene, vol. 27, no. 3, Article ID 1210647, 8 pages, 2007 - The needle in the haystack: Application of breast fine-needle aspirate samples to quantitative protein microarray technology
Cancer, vol. 111, no. 3, pp. 173–184, 2007 - Reply:
Hepatology, vol. 46, no. 4, pp. 1306–1307, 2007 - A method for the selective isolation and enrichment of carrier protein-bound low-molecular weight proteins and peptides in the blood
PROTEOMICS – Clinical Applications, vol. 1, no. 2, pp. 176–184, 2007 - Physicochemically modified silicon as a substrate for protein microarrays
Biomaterials, vol. 28, no. 3, pp. 550–558, 2007 - Genomic and Proteomic Profiles Reveal the Association of Gelsolin to TP53 Status and Bladder Cancer Progression
American Journal Of Pathology, vol. 171, no. 5, pp. 1650–1658, 2007 - Serum Proteomic Analysis Identifies a Highly Sensitive and Specific Discriminatory Pattern in Stage 1 Breast Cancer
Annals of Surgical Oncology, vol. 14, no. 9, pp. 2470–2476, 2007 - A Novel, High-Throughput Workflow for Discovery and Identification of Serum Carrier Protein-Bound Peptide Biomarker Candidates in Ovarian Cancer Samples
Clinical Chemistry, vol. 53, no. 6, pp. 1067–1074, 2007 - Putting the "Bio" back into Biomarkers: Orienting Proteomic Discovery toward Biology and away from the Measurement Platform
Clinical Chemistry, vol. 54, no. 1, pp. 3–5, 2007 - Reverse-phase protein microarrays: application to biomarker discovery and translational medicine
Expert Review of Molecular Diagnostics, vol. 7, no. 5, pp. 625–633, 2007 - Mathematical Modeling of the Cancer Cell’s Control Circuitry: Paving the Way to Individualized Therapeutic Strategies
Current Signal Transduction Therapy, vol. 2, no. 2, pp. 145–155, 2007 - Combination of SELDI-TOF-MS and Data Mining Provides Early-stage Response Prediction for Rectal Tumors Undergoing Multimodal Neoadjuvant Therapy
Annals of Surgery, vol. 245, no. 2, pp. 259–266, 2007 - Differentiation of tumour-stage mycosis fungoides, psoriasis vulgaris and normal controls in a pilot study using serum proteomic analysis
British Journal of Dermatology, vol. 157, no. 5, pp. 946–953, 2007 - Phosphoprotein Pathway Mapping: Akt/Mammalian Target of Rapamycin Activation Is Negatively Associated with Childhood Rhabdomyosarcoma Survival
Cancer Research, vol. 67, no. 7, pp. 3431–3440, 2007 - Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
Molecular Cancer Therapeutics, vol. 6, no. 3, pp. 820–832, 2007 - Lysophosphatidic Acid Down-Regulates Stress Fibers and Up-Regulates Pro-Matrix Metalloproteinase-2 Activation in Ovarian Cancer Cells
Molecular Cancer Research, vol. 5, no. 2, pp. 121–131, 2007 - Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans
Blood, vol. 110, no. 2, pp. 501–508, 2007 - Discovering Clinical Biomarkers of Ionizing Radiation Exposure with Serum Proteomic Analysis
Cancer Research, vol. 66, no. 3, pp. 1844–1850, 2006 - Breast Cancer Growth Prevention by Statins
Cancer Research, vol. 66, no. 17, pp. 8707–8714, 2006 - Secreted Neutral Metalloproteases of Bacillus anthracis as Candidate Pathogenic Factors
Journal of Biological Chemistry, vol. 281, no. 42, pp. 31408–31418, 2006 - Dynamic Profiling of the Post-translational Modifications and Interaction Partners of Epidermal Growth Factor Receptor Signaling after Stimulation by Epidermal Growth Factor Using Extended Range Proteomic Analysis (ERPA)
Molecular & Cellular Proteomics, vol. 5, no. 9, pp. 1610–1627, 2006 - Role of proteomics in personalized medicine
Personalized Medicine, vol. 3, no. 3, pp. 223–226, 2006 - Clinical phosphoproteomic profiling for personalized targeted medicine using reverse phase protein microarray
Targeted Oncology, vol. 1, no. 3, pp. 151–167, 2006 - Nanoparticles: potential biomarker harvesters
Current Opinion in Chemical Biology, vol. 10, no. 1, pp. 56–61, 2006 - The amplified peptidome: the new treasure chest of candidate biomarkers
Current Opinion in Chemical Biology, vol. 10, no. 1, pp. 50–55, 2006 - Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer
The Journal of Pathology, vol. 208, no. 5, pp. 595–606, 2006 - Technology Insight: pharmacoproteomics for cancer—promises of patient-tailored medicine using protein microarrays
Nature Clinical Practice Oncology, vol. 3, no. 5, Article ID ncponc0485, 12 pages, 2006 - Laser-capture microdissection
Nature Protocols, vol. 1, no. 2, Article ID nprot.2006.85, 17 pages, 2006 - The blood peptidome: a higher dimension of information content for cancer biomarker discovery
Nature Reviews Cancer, vol. 6, no. 12, Article ID nrc2011, 6 pages, 2006 - Journal of Proteome Research, vol. 5, no. 5, pp. 1261–1266, 2006
- Accurate diagnosis of acute graft-versus-host disease using serum proteomic pattern analysis
Experimental Hematology, vol. 34, no. 6, pp. 796–801, 2006 - Selective binding and enrichment for low-molecular weight biomarker molecules in human plasma after exposure to nanoporous silica particles
PROTEOMICS, vol. 6, no. 11, pp. 3243–3250, 2006 - Protein pathway analysis in Clinical Proteomics using protein microarrays
Drug Discovery Today: Technologies, vol. 2, no. 4, pp. 353–359, 2005 - Bioconjugate Chemistry, vol. 16, no. 3, pp. 559–566, 2005
- Clinical Proteomics: From Biomarker Discovery and Cell Signaling Profiles to Individualized Personal Therapy
Bioscience Reports, vol. 25, no. 1-2, pp. 107–125, 2005 - A serum proteomic approach to gauging the state of remission in Wegener's granulomatosis
Arthritis & Rheumatism, vol. 52, no. 3, pp. 902–910, 2005 - Kinase substrate protein microarray analysis of human colon cancer and hepatic metastasis
Clinica Chimica Acta, vol. 357, no. 2, pp. 180–183, 2005 - A mathematical model of combination therapy using the EGFR signaling network
Biosystems, vol. 80, no. 1, pp. 57–69, 2005 - Analysis of Albumin-Associated Peptides and Proteins from Ovarian Cancer Patients
Clinical Chemistry, vol. 51, no. 10, pp. 1933–1945, 2005 - CSF proteome: a protein repository for potential biomarker identification
Expert Review of Proteomics, vol. 2, no. 1, pp. 57–70, 2005 - Cancer proteomics: many technologies, one goal
Expert Review of Proteomics, vol. 2, no. 5, pp. 693–703, 2005 - Mapping Molecular Networks Using Proteomics: A Vision for Patient-Tailored Combination Therapy
Journal of Clinical Oncology, vol. 23, no. 15, pp. 3614–3621, 2005 - Low molecular weight proteomic information distinguishes metastatic from benign pheochromocytoma
Endocrine Related Cancer, vol. 12, no. 2, pp. 263–272, 2005 - Use of Reverse Phase Protein Microarrays and Reference Standard Development for Molecular Network Analysis of Metastatic Ovarian Carcinoma
Molecular & Cellular Proteomics, vol. 4, no. 4, pp. 346–355, 2005 - Pathology of the Future: Molecular Profiling for Targeted Therapy
Cancer Investigation, vol. 23, no. 1, pp. 36–46, 2005 - Analysis of mass spectral serum profiles for biomarker selection
Bioinformatics, vol. 21, no. 21, pp. 4039–4045, 2005 - Importance of Communication Between Producers and Consumers of Publicly Available Experimental Data
CancerSpectrum Knowledge Environment, vol. 97, no. 4, pp. 310–314, 2005 - Proteomic Analysis of Apoptotic Pathways Reveals Prognostic Factors in Follicular Lymphoma
Clinical Cancer Research, vol. 11, no. 16, pp. 5847–5855, 2005 - Modeling of Protein Signaling Networks in Clinical Proteomics
Cold Spring Harbor Symposia on Quantitative Biology, vol. 70, no. 1, pp. 517–524, 2005 - Supra-additive Growth Inhibition by a Celecoxib Analogue and Carboxyamido-triazole Is Primarily Mediated through Apoptosis
Cancer Research, vol. 65, no. 9, pp. 3853–3860, 2005 - Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment
Journal of Clinical Investigation, vol. 115, no. 5, pp. 1163–1176, 2005 - Serum peptidome for cancer detection: spinning biologic trash into diagnostic gold
Journal of Clinical Investigation, vol. 116, no. 1, pp. 26–30, 2005 - Clinical Proteomics and Biomarker Discovery
Annals of the New York Academy of Sciences, vol. 1022, no. 1, pp. 295–305, 2004 - Serum Proteomics in Cancer Diagnosis and Management *
Annual Review of Medicine, vol. 55, no. 1, pp. 97–112, 2004 - Blasting into the Microworld of Tissue Proteomics: A New Window on Cancer: Commentary re S. A. Schwartz et al., Protein Profiling in Brain Tumors Using Mass Spectrometry: Feasibility of a New Technique for the Analysis of Protein Expression. Clin. Cancer Res., 10: 981-987, 2004.
Clinical Cancer Research, vol. 10, no. 3, pp. 825–827, 2004 - SERUM PROTEOMIC PROFILING CAN DISCRIMINATE PROSTATE CANCER FROM BENIGN PROSTATES IN MEN WITH TOTAL PROSTATE SPECIFIC ANTIGEN LEVELS BETWEEN 2.5 AND 15.0 NG/ML
The Journal of Urology, vol. 172, no. 4, pp. 1302–1305, 2004 - Toxicoproteomics: Serum Proteomic Pattern Diagnostics for Early Detection of Drug Induced Cardiac Toxicities and Cardioprotection
Toxicologic Pathology, vol. 32, no. 6, pp. 122–130, 2004 - Molecular Profiling of Cancer
Toxicologic Pathology, vol. 32, no. 6, pp. 67–71, 2004 - Application of Laser Capture Microdissection and Protein MicroArray Technologies in the Molecular Analysis of Airway Injury Following Pollution Particle Exposure
Journal of Toxicology and Environmental Health Part A, vol. 67, no. 11, pp. 851–861, 2004 - Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray
Laboratory Investigation, vol. 84, no. 2, Article ID 3700051, 9 pages, 2004 - Use of proteomic analysis to monitor responses to biological therapies
Expert Opinion on Biological Therapy, vol. 4, no. 1, pp. 83–93, 2004 - High-resolution serum proteomic features for ovarian cancer detection
Endocrine Related Cancer, vol. 11, no. 2, pp. 163–178, 2004 - High-resolution serum proteomic patterns for ovarian cancer detection
Endocrine Related Cancer, vol. 11, no. 4, pp. 583–584, 2004 - Clarification in the Point/Counterpoint Discussion Related to Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometric Identification of Patients with Adenocarcinomas of the Prostate * Proteomic Pattern Complexity Reveals a Rich and Uncharted Continent of Biomarkers
Clinical Chemistry, vol. 50, no. 8, pp. 1475–1477, 2004 - SELDI-TOF-based serum proteomic pattern diagnostics for early detection of cancer
Current Opinion in Biotechnology, vol. 15, no. 1, pp. 24–30, 2004 - Network-targeted combination therapy: a new concept in cancer treatment
Drug Discovery Today: Therapeutic Strategies, vol. 1, no. 4, pp. 425–433, 2004 - Lessons from Kitty Hawk: From feasibility to routine clinical use for the field of proteomic pattern diagnostics
PROTEOMICS, vol. 4, no. 8, pp. 2357–2360, 2004 - Mitochondrial proteome: Cancer-altered metabolism associated with cytochromec oxidase subunit level variation
PROTEOMICS, vol. 4, no. 9, pp. 2789–2795, 2004 - An investigation into the human serum“interactome”
ELECTROPHORESIS, vol. 25, no. 9, pp. 1289–1298, 2004 - Proteomic analysis of lymph
PROTEOMICS, vol. 4, no. 3, pp. 753–765, 2004 - Profiling the activity of G proteins in patient-derived tissues by rapid affinity-capture of signal transduction proteins (GRASP)
PROTEOMICS, vol. 4, no. 3, pp. 812–818, 2004 - Molecular Technologies for Personalized Cancer Management
JAMA: The Journal of the American Medical Association, vol. 291, no. 13, pp. 1644–1645, 2004 - Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
Cancer Cell, vol. 5, no. 1, pp. 103–103, 2004 - Journal of Proteome Research, vol. 3, no. 2, pp. 209–217, 2004
- Opportunities for Nanotechnology-Based Innovation in Tissue Proteomics
Biomedical Microdevices, vol. 6, no. 3, pp. 231–239, 2004 - Genomic and proteomic technologies for individualisation and improvement of cancer treatment
European Journal of Cancer, vol. 40, no. 17, pp. 2623–2632, 2004 - Biomarkers of ovarian tumours
European Journal of Cancer, vol. 40, no. 17, pp. 2604–2612, 2004 - Importance of disclosure of patent applications
The Lancet, vol. 364, no. 9434, pp. 577–578, 2004 - Department of Error
The Lancet, vol. 364, no. 9434, p. 582, 2004 - Trapping radioactive carbon dioxide during cellular metabolic assays under standard culture conditions: description of a unique gas-capturing device
Journal of Biochemical and Biophysical Methods, vol. 58, no. 2, pp. 119–124, 2004 - Protein microarray detection strategies: focus on direct detection technologies
Journal of Immunological Methods, vol. 290, no. 1-2, pp. 121–133, 2004 - Proteomic approaches in cancer risk and response assessment
Trends in Molecular Medicine, vol. 10, no. 2, pp. 59–64, 2004 - Use of proteomic patterns to screen for gastrointestinal malignancies
Surgery, vol. 135, no. 3, pp. 243–247, 2004 - Clinical proteomics: Applications for prostate cancer biomarker discovery and detection
Urologic Oncology: Seminars and Original Investigations, vol. 22, no. 4, pp. 322–328, 2004 - Protein microarrays: Meeting analytical challenges for clinical applications
Cancer Cell, vol. 3, no. 4, pp. 317–325, 2003 - Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
Cancer Cell, vol. 4, no. 6, pp. 437–450, 2003 - Signal pathway profiling of ovarian cancer from human tissue specimens using reverse-phase protein microarrays
PROTEOMICS, vol. 3, no. 11, pp. 2085–2090, 2003 - Protein microarrays: Molecular profiling technologies for clinical specimens
PROTEOMICS, vol. 3, no. 11, pp. 2091–2100, 2003 - Signal pathway profiling of prostate cancer using reverse phase protein arrays
PROTEOMICS, vol. 3, no. 11, pp. 2142–2146, 2003 - Evaluation of ethanol-fixed, paraffin-embedded tissues for proteomic applications
PROTEOMICS, vol. 3, no. 4, pp. 413–421, 2003 - Mitochondrial proteome: Altered cytochromec oxidase subunit levels in prostate cancer
PROTEOMICS, vol. 3, no. 9, pp. 1801–1810, 2003 - Molecular diagnostics: an FDA perspective
Expert Review of Molecular Diagnostics, vol. 3, no. 2, pp. 129–140, 2003 - Cancer diagnosis using proteomic patterns
Expert Review of Molecular Diagnostics, vol. 3, no. 4, pp. 411–420, 2003 - Mass Spectrometry-based Diagnostics: The Upcoming Revolution in Disease Detection
Clinical Chemistry, vol. 49, no. 4, pp. 533–534, 2003 - Drosophila screening model for metastasis: Semaphorin 5c is required for l(2)gl cancer phenotype
Proceedings of the National Academy of Sciences, vol. 100, no. 20, pp. 11463–11468, 2003 - Utility of reverse phase protein arrays: Applications to signalling pathways and human body arrays
Briefings in Functional Genomics and Proteomics, vol. 1, no. 3, pp. 305–315, 2002 - Proteomic Evaluation of Archival Cytologic Material Using SELDI Affinity Mass Spectrometry Potential for Diagnostic Applications
American Journal of Clinical Pathology, vol. 118, no. 6, pp. 870–876, 2002 - Proteomic analysis of human prostate cancer
Molecular Carcinogenesis, vol. 33, no. 1, pp. 9–15, 2002 - Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer
PROTEOMICS, vol. 2, no. 1, pp. 76–84, 2002 - Genomics and proteomics: application of novel technology to early detection and prevention of cancer
Cancer Detection and Prevention, vol. 26, no. 4, pp. 249–255, 2002 - Use of proteomic patterns in serum to identify ovarian cancer
The Lancet, vol. 359, no. 9306, pp. 572–577, 2002 - Journal of Mammary Gland Biology and Neoplasia, vol. 7, no. 4, pp. 433–440, 2002
- Clinical proteomics: translating benchside promise into bedside reality
Nature Reviews Drug Discovery, vol. 1, no. 9, Article ID nrd891, 12 pages, 2002 - Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
Oncogene, vol. 20, no. 16, Article ID 1204265, 8 pages, 2001 - Molecular profiling of cancer and drug-induced toxicity using new proteomic technologies
Current Therapeutic Research, vol. 62, no. 11, pp. 803–819, 2001 - New technologies for biomarker analysis of prostate cancer progression: Laser capture microdissection and tissue proteomics
Urology, vol. 57, no. 4, pp. 160–163, 2001 - Clinical Proteomics: Personalized Molecular Medicine
JAMA: The Journal of the American Medical Association, vol. 286, no. 18, pp. 2211–2214, 2001 - Fingerprinting of signal transduction pathways using a combination of anti-phosphotyrosine immunoprecipitations and two-dimensional polyacrylamide gel electrophoresis
ELECTROPHORESIS, vol. 22, no. 10, pp. 2120–2124, 2001 - New approaches to proteomic analysis of breast cancer
PROTEOMICS, vol. 1, no. 10, pp. 1205–1215, 2001 - Proteomic profiling of the cancer microenvironment by antibody arrays
PROTEOMICS, vol. 1, no. 10, pp. 1271–1278, 2001 - 2D Differential In-gel Electrophoresis for the Identification of Esophageal Scans Cell Cancer-specific Protein Markers
Molecular & Cellular Proteomics, vol. 1, no. 2, pp. 117–123, 2001 - Rapid protein display profiling of cancer progression directly from human tissue using a protein biochip
Drug Development Research, vol. 49, no. 1, pp. 34–42, 2000 - An approach to proteomic analysis of human tumors
Molecular Carcinogenesis, vol. 27, no. 3, pp. 158–165, 2000 - Proteomic analysis of laser capture microdissected human prostate cancer andin vitro prostate cell lines
Electrophoresis, vol. 21, no. 11, pp. 2235–2242, 2000 - Laser capture microdissection: Beyond functional genomics to proteomics
Molecular Diagnosis, vol. 5, no. 4, pp. 301–307, 2000 - Breast Cancer Research, vol. 2, no. 1, p. 13, 1999
- Activation of Raf-1 by Interferon gamma and Oncostatin M Requires Expression of the Stat1 Transcription Factor
Journal of Biological Chemistry, vol. 273, no. 30, pp. 18701–18704, 1998 - Phosphorylation Events Modulate the Ability of Interferon Consensus Sequence Binding Protein to Interact with Interferon Regulatory Factors and to Bind DNA
Journal of Biological Chemistry, vol. 272, no. 15, pp. 9785–9792, 1997 - Nature, vol. 390, no. 6660, pp. 629–632, 1997
- Interleukin 12 Induces Tyrosine Phosphorylation and Activation of STAT4 in Human Lymphocytes
Proceedings of the National Academy of Sciences, vol. 92, no. 16, pp. 7307–7311, 1995 - Prolactin Activates the Interferon-Regulated p91 Transcription Factor and the Jak2 Kinase by Tyrosine Phosphorylation
Proceedings of the National Academy of Sciences, vol. 91, no. 15, pp. 7174–7178, 1994 - Interferon-alpha-induced gene expression: Evidence for a selective effect of ouabain on activation of the ISGF3 transcription complex
Virology, vol. 190, no. 1, pp. 210–220, 1992