Dennis Sgroi

Personal Home Page

http://www.dfhcc.harvard.edu/membership/member-profile/member/245/0/

Articles in Scholarly Journals [Incomplete List]

  1. Hypoxia regulates TSC1/2 mTOR signaling and tumor suppression through REDD1-mediated 14 3 3 shuttling
    Genes & Development, vol. 22, no. 2, pp. 239–251, 2008
  2. A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors
    Genes & Development, vol. 21, no. 17, pp. 2131–2136, 2007
  3. HOXB13 promotes ovarian cancer progression
    Proceedings of the National Academy of Sciences, vol. 104, no. 43, pp. 17093–17098, 2007
  4. Genetic and functional analysis ofCHEK2 (CHK2) variants in multiethnic cohorts
    International Journal of Cancer, vol. 121, no. 12, pp. 2661–2667, 2007
  5. Predictors of Resistance to Preoperative Trastuzumab and Vinorelbine for HER2-Positive Early Breast Cancer
    Clinical Cancer Research, vol. 13, no. 4, pp. 1198–1207, 2007
  6. The Prognostic Biomarkers HOXB13, IL17BR, and CHDH Are Regulated by Estrogen in Breast Cancer
    Clinical Cancer Research, vol. 13, no. 21, pp. 6327–6334, 2007
  7. The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers
    Journal of Clinical Investigation, vol. 117, no. 5, pp. 1370–1380, 2007
  8. Gene Expression of Purified  -Cell Tissue Obtained from Human Pancreas with Laser Capture Microdissection
    Journal of Clinical Endocrinology & Metabolism, vol. 93, no. 3, pp. 1046–1053, 2007
  9. Prospective Study of Wide Excision Alone for Ductal Carcinoma in Situ of the Breast
    Journal of Clinical Oncology, vol. 24, no. 7, pp. 1031–1036, 2006
  10. The HOXB13:IL17BR Expression Index Is a Prognostic Factor in Early-Stage Breast Cancer
    Journal of Clinical Oncology, vol. 24, no. 28, pp. 4611–4619, 2006
  11. Breast Cancer Research, vol. 8, no. 6, p. R73, 2006
  12. A Two-Gene Expression Ratio of Homeobox 13 and Interleukin-17B Receptor for Prediction of Recurrence and Survival in Women Receiving Adjuvant Tamoxifen
    Clinical Cancer Research, vol. 12, no. 7, pp. 2080–2087, 2006
  13. Epidermal Growth Factor Receptor Kinase Domain Mutations in Esophageal and Pancreatic Adenocarcinomas
    Clinical Cancer Research, vol. 12, no. 14, pp. 4283–4287, 2006
  14. Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection
    Diabetologia, vol. 50, no. 2, pp. 334–342, 2006
  15. Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
    Proceedings of the National Academy of Sciences, vol. 103, no. 7, pp. 2316–2321, 2006
  16. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
    Proceedings of the National Academy of Sciences, vol. 103, no. 33, pp. 12405–12410, 2006
  17. The Spemann organizer gene, Goosecoid, promotes tumor metastasis
    Proceedings of the National Academy of Sciences, vol. 103, no. 50, pp. 18969–18974, 2006
  18. Frequent Met Oncogene Amplification in a Brca1/Trp53 Mouse Model of Mammary Tumorigenesis
    Cancer Research, vol. 66, no. 7, pp. 3452–3455, 2006
  19. Identification of Cyclin D1- and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression
    Cancer Research, vol. 66, no. 24, pp. 11649–11658, 2006
  20. Response of Some Head and Neck Cancers to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors May Be Linked to Mutation of ERBB2 rather than EGFR
    Clinical Cancer Research, vol. 11, no. 22, pp. 8105–8108, 2005
  21. G1/S Cell Cycle Arrest Provides Anoikis Resistance through Erk-Mediated Bim Suppression
    Molecular and Cellular Biology, vol. 25, no. 12, pp. 5282–5291, 2005
  22. Novel Role for PDEF in Epithelial Cell Migration and Invasion
    Cancer Research, vol. 65, no. 24, pp. 11572–11580, 2005
  23. Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
    Cell, vol. 121, no. 3, pp. 335–348, 2005
  24. Case 24-2005 - A 58-Year-Old Woman with Early-Stage Estrogen-Receptor-Positive Breast Cancer
    New England Journal of Medicine, vol. 353, no. 6, pp. 617–622, 2005
  25. Mapping Molecular Networks Using Proteomics: A Vision for Patient-Tailored Combination Therapy
    Journal of Clinical Oncology, vol. 23, no. 15, pp. 3614–3621, 2005
  26. Epidermal Growth Factor Receptor Mutations and Gene Amplification in Non-Small-Cell Lung Cancer: Molecular Analysis of the IDEAL/INTACT Gefitinib Trials
    Journal of Clinical Oncology, vol. 23, no. 31, pp. 8081–8092, 2005
  27. Laser Capture Microdissection: a rising tool in genetic profiling of cancer
    Expert Review of Molecular Diagnostics, vol. 4, no. 4, pp. 429–430, 2004
  28. Sclerosing lesions of the breast
    Seminars in Diagnostic Pathology, vol. 21, no. 1, pp. 42–47, 2004
  29. Journal of Proteome Research, vol. 3, no. 3, pp. 604–612, 2004
  30. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    Cancer Cell, vol. 5, no. 6, pp. 607–616, 2004
  31. REA two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    Cancer Cell, vol. 6, no. 5, p. 445, 2004
  32. The effect of tumor size and lymph node status on breast carcinoma lethality
    Cancer, vol. 98, no. 10, pp. 2133–2143, 2003
  33. Laser Capture Microdissection and Advanced Molecular Analysis of Human Breast Cancer
    Journal of Mammary Gland Biology and Neoplasia, vol. 8, no. 3, pp. 335–345, 2003
  34. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
    Nature Cell Biology, vol. 5, no. 8, Article ID ncb1026, 7 pages, 2003
  35. Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein
    Genes & Development, vol. 17, no. 17, pp. 2094–2107, 2003
  36. Gene expression profiles of human breast cancer progression
    Proceedings of the National Academy of Sciences, vol. 100, no. 10, pp. 5974–5979, 2003
  37. Genetic Regulation of Metabolic Pathways in beta -Cells Disrupted by Hyperglycemia
    Journal of Biological Chemistry, vol. 277, no. 13, pp. 10912–10921, 2002
  38. Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation
    Genes & Development, vol. 16, no. 17, pp. 2252–2263, 2002
  39. HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells
    Proceedings of the National Academy of Sciences, vol. 98, no. 17, pp. 9796–9801, 2001
  40. BACH1, a Novel Helicase-like Protein, Interacts Directly with BRCA1 and Contributes to Its DNA Repair Function
    Cell, vol. 105, no. 1, pp. 149–160, 2001
  41. New approaches to proteomic analysis of breast cancer
    PROTEOMICS, vol. 1, no. 10, pp. 1205–1215, 2001
  42. Increased Expression of Antioxidant and Antiapoptotic Genes in Islets That May Contribute to  -Cell Survival During Chronic Hyperglycemia
    Diabetes, vol. 51, no. 2, pp. 413–423, 2001
  43. Germ-Line BRCA1 Mutations in Jewish and Non-Jewish Women with Early-Onset Breast Cancer
    New England Journal of Medicine, vol. 334, no. 3, pp. 143–149, 1996
  44. A Single N-linked Glycosylation Site Is Implicated in the Regulation of Ligand Recognition by the I-type Lectins CD22 and CD33
    Journal of Biological Chemistry, vol. 271, no. 31, pp. 18803–18809, 1996
  45. Regulation of CD45 Engagement by the B-Cell Receptor CD22
    Proceedings of the National Academy of Sciences, vol. 92, no. 9, pp. 4026–4030, 1995
  46. CD22 binds to α-2,6-sialyltransferase-dependent epitopes on COS cells
    Cell, vol. 68, no. 6, pp. 1003–1004, 1992
  47. The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and $alpha;2?6 sialyltransferase, CD75, on B cells
    Cell, vol. 66, no. 6, pp. 1133–1144, 1991
  48. Effects of H-7 are not exclusively mediated through protein kinase C or the cyclic nucleotide-dependent kinases
    Biochemical and Biophysical Research Communications, vol. 162, no. 1, pp. 138–143, 1989
  49. T cell receptor beta chain gene rearrangement shared by murine T cell lines derived from a site of autoimmune inflammation.
    Journal of Clinical Investigation, vol. 81, no. 6, pp. 1810–1818, 1988
  50. The protein kinase C inhibitor H-7, inhibits antigen and IL-2-induced proliferation of murine T cell lines
    Biochemical and Biophysical Research Communications, vol. 145, no. 2, pp. 666–672, 1987